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Other groups have developed ways of building up
tissues layer by layer (New Scientist, 4 January, p
19), but none is as simple and quick as printing.
Most tissue engineers first create a degradable
scaffold and then seed it with cells. This technique
can be used to create complex shapes, such as the
infamous “ear on a mouse”, but placing different
cell types precisely is very difficult. |
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Mironov and Boland hope it will be possible to print the
entire network of arteries, capillaries and veins that
nourish organs. But to keep cells alive, the organs
would have to be completed within a couple of hours and
a growth medium circulated through the fragile new
vessels. Large structures might not be strong enough to
hold together if the gel is removed after such a short
period. However, the team is already experimenting with
adding substances such as the skin protein collagen to
speed fusion and reinforce structures.
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